K.K.Wijesundara

Dr. K.K.Wijesundara

BVSc(Peradeniya),PhD (Osaka Prefecture,Japan)
Senior Lecturer
Address:

Department of Veterinary Pathobiology,
Faculty of Veterinary Medicine & Animal Science,
University of Peradeniya,
Peradeniya,20400

Contact:

Phone:+094 812395861(office)
Email: kavindra@vet.pdn.ac.lk
kavindra77@gmail.com

  • Veterinary Pathology
    • Experimental and Toxicologic Pathology
    • Molecular pathogenesis of toxic-induced diseases
    Publications(After 2018):
      • Ranasinghe, K. N. K., A. D. Premarathna, T. A. N. Mahakapuge, K. K. Wijesundera, A. T. Ambagaspitiya, A. P. Jayasooriya, S. A. M. Kularatne, and R. P. V. J. Rajapakse. "In vivo anticancer effects of Momordica charantia seed fat on hepatocellular carcinoma in a rat model." Journal of Ayurveda and Integrative Medicine 12, no. 3 (2021): 435-442.

      • Sharma, U. N. S., Fernando, D. D., Wijesundara, K. K., Manawadu, A., Pathirana, I., & Rajapakse, R. J. (2021). Anticoccidial effects of Phyllanthus emblica (Indian gooseberry) extracts: potential for controlling avian coccidiosis. Veterinary Parasitology: Regional Studies and Reports, 25, 100592.

      • Jayasumana, M. T. L. K., D. M. U. N. K. Dunuwila, P. G. A. S. Palkumbura, R. Mudalige, I. V. P. Dharmawardana, R. R. M. K. K. Wijesundera, and H. R. N. Jinadasa. "Detection of Mycobacterium bovis in cattle lungs from two abattoirs in Western and North Central provinces of Sri Lanka." Journal of the National Science Foundation of Sri Lanka 49, no. 1 (2021).

      • Bogahawaththa, Sudarma, Suranga P. Kodithuwakku, Kavindra K. Wijesundera, Eranga H. Siriweera, Lalith Jayasinghe, Waruna L. Dissanayaka, Jayanthe Rajapakse, Chandana B. Herath, Tadayuki Tsujita, and Missaka PB Wijayagunawardane. "Anti-fibrotic and anti-angiogenic activities of Osbeckia octandra leaf extracts in thioacetamide-induced experimental liver cirrhosis." Molecules 26, no. 16 (2021): 4836.

      • Dangolla, A., D. L. R. Wijesundara, D. Blair, D. D. Fernando, K. K. Wijesundera, W. G. D. Chathuranga, W. A. P. P. de Silva, and R. S. Rajakaruna. "Canine trypanosomosis in Sri Lanka: An emerging problem reported from three distinct geographic locations." Parasitology International 77 (2020): 102129.

      • Premarathna, Amal D., T. H. Ranahewa, S. K. Wijesekera, D. L. Harishchandra, K. J. K. Karunathilake, Roshitha N. Waduge, R. R. M. K. K. Wijesundara, Anura P. Jayasooriya, Viskam Wijewardana, and R. P. V. J. Rajapakse. "Preliminary screening of the aqueous extracts of twenty-three different seaweed species in Sri Lanka with in-vitro and in-vivo assays." Heliyon 6, no. 6 (2020): e03918.

      • Premarathna, Amal D., T. H. Ranahewa, S. K. Wijesekera, R. R. M. K. K. Wijesundara, Anura P. Jayasooriya, Viskam Wijewardana, and R. P. V. J. Rajapakse. "Wound healing properties of aqueous extracts of Sargassum illicifolium: An in vitro assay." Wound Medicine 24, no. 1 (2019): 1-7.

      Publications(Selected):
        • M1-/M2-macrophage polarization in pseudolobules consisting of adipohilin-rich hepatocytes in thioacetamide (TAA)-induced rat hepatic cirrhosis. Wijesundera KK, Izawa T, Tennakoon AH, Golbar HM, Tanaka M, Kuwamura M, Yamate J. Exp Mol Pathol. 2016; 101:133-42.

        • Depletion of Hepatic Macrophages Aggravates Liver Lesions Induced in Rats by Thioacetamide (TAA). Golbar HM, Izawa T, Wijesundera KK, Bondoc A, Tennakoon AH, Kuwamura M, Yamate J. Toxicol Pathol. 2016; 4:246-58.

        • M1-/M2-macrophages contribute to the development of GST-P-positive preneoplastic lesions in chemically-induced rat cirrhosis. Wijesundera KK, Izawa T, Tennakoon AH, Golbar HM, Tanaka M, Kuwamura M, Yamate J. Exp Toxicol Pathol. 2015; 67:467-75.

        • Immunohistochemical characterization of glial fibrillary acidic protein (GFAP)-expressing cells in a rat liver cirrhosis model induced by repeated injections of thioacetamide (TAA). Tennakoon AH, Izawa T, Wijesundera KK, Murakami H, Katou-Ichikawa C, Tanaka M, Golbar HM, Kuwamura M, Yamate J. Exp Toxicol Pathol. 2015; 67: 53-63.

        • M1- and M2-macrophage polarization in thioacetamide (TAA)-induced rat liver lesions; a possible analysis for hepato-pathology. Wijesundera KK, Izawa T, Murakami H, Tennakoon AH, Golbar HM, Kato-Ichikawa C, Tanaka M, Kuwamura M, Yamate J. Histol Histopathol. 2014; 29: 497-511.

        • M1- and M2-macrophage polarization in rat liver cirrhosis induced by thioacetamide (TAA), focusing on Iba1 and galectin-3. Wijesundera KK, Izawa T, Tennakoon AH, Murakami H, Golbar HM, Katou-Ichikawa C, Tanaka M, Kuwamura M, Yamate J. Exp Mol Pathol. 2014; 96: 382-92

        • Inflammatory regulation of iron metabolism during thioacetamide-induced acute liver injury in rats. Izawa T, Murakami H, Wijesundera KK, Golbar HM, Kuwamura M, Yamate J. Exp Toxicol Pathol. 2014; 66: 155-62.

        • Expression of nestin in remodelling of α-naphthylisothiocyanate-induced acute bile duct injury in rats. Golbar HM, Izawa T, Wijesundera KK, Tennakoon AH, Katou-Ichikawa C, Tanaka M, Kuwamura M, Yamate J. J Comp Pathol. 2014 Aug-Oct;151(2-3):255-63.

        • Expressions of Iba1 and galectin-3 (Gal-3) in thioacetamide (TAA)-induced acute rat liver lesions. Wijesundera KK, Juniantito V, Golbar HM, Fujisawa K, Tanaka M, Ichikawa C, Izawa T, Kuwamura M, Yamate J. Exp Toxicol Pathol. 2013; 65: 799-808.

        • Spontaneous Extraskeletal Osteosarcoma in a Rabbit (Oryctolagus cuniculus): Histopathological and Immunohistochemical Findings. Wijesundera KK, Izawa T, Fujita D, Denda Y, Seto E, Sasai H, Kuwamura M, Yamate J. J Toxicol Pathol. 2013; 26: 309-12.

        • Characterization of glial fibrillary acidic protein (GFAP)-expressing hepatic stellate cells and myofibroblasts in thioacetamide (TAA)-induced rat liver injury. Tennakoon AH, Izawa T, Wijesundera KK, Golbar HM, Tanaka M, Ichikawa C, Kuwamura M, Yamate J. Exp Toxicol Pathol. 2013; 65: 1159-71.

        • Pulmonary dystrophic oxalosis and its possible relation to fibrosis in an aged Gentoo penguin (Pygoscelis papua). Wijesundera KK, Izawa T, Tanaka M, Nakao T, Maezono Y, Ito S, Kuwamura M, Yamate J. J Vet Med Sci. 2013; 75: 365-8.