Anuruddhika Dissanayake

Prof. D.R. Anuruddhika Dissanayake

BVSc(Peradeniya),PhD
Professor
Address:

Department Veterinary Clinical Science,
Faculty of Veterinary Medicine & Animal Science,
University of Peradeniya,
Peradeniya,20400

Contact:

Phone:+94812395756/+94718105148
Email:anuruddhika@vet.pdn.ac.lk
drad199@gmail.com

  • Perumal Pellei award for the best research paper published in 2016 in Sri Lanka Veterinary Journal”
  • Award for the best paper in Fish and Wildlife at 63rd Annual Scientific Sessions of the Sri Lanka Veterinary Association in 2011 for the paper titled, Mycobacteriosis: an emerging disease in guppies in Sri Lanka
  • NRC Merit award for the scientific research published in the year 2010
  • Award for the best paper in Animal Health at the 62nd Annual Scientific Sessions of the Sri Lanka Veterinary Association in year 2010 for the paper titled, Isolation, identification and in vitro antibacterial susceptibility of Aeromonas species causing septicaemia in fresh water ornamental fish in Sri Lanka.
  • Award for the best paper in Animal Health at the 61st Annual Scientific Sessions of the Sri Lanka Veterinary Association in year 2009 for the paper titled, Prepartum Intra-mammary infection (IMI) in heifers of up-country dairy farms” .
  • Presidential award for the scientific research published in the year 2008.
  • Certificate of commendation for the outstanding merit carried out on NSF supported grant “determination of core types of lipopolysaccharide of avian pathogenic E. coli and their immunogenicity
  • Commonwealth split-site doctoral scholarship (year 2006-2007) to conduct postgraduate studies at University of Edinburgh, UK.
  • Commendable presentation, University Research Session 2003, for the paper titled “Identification of pathogenic Escherichia coli associated with poultry”.
  • Commendable presentation, University Research Session 2003, for the paper titled “A serological and biochemical characterization of Salmonella from poultry at the microbiology diagnostic laboratory.
  • Conducting lectures in Companion, Wild and Zoo animal Medicine particularly on infectious and immune mediated disease, vector borne diseases, vaccinology, renal diseases, Dermatology and diagnostic techniques.

  • Infectious and immune mediated diseases affecting companion animals
  • Genetic mechanisms of virulence and antimicrobial resistance of pathogenic bacteria
  • Phylogenetic analysis of microbes
  • Novel vaccines to prevent bacterial infections in animal
  • Leukaemia in humans and animals

Position Current Completed
Project leader 1 2
Co-investigator 3

Completed projects
  • Project Title: Identification of canine Parvo virus (CPV) variants present in Sri Lanka and determine the efficacy of current vaccines and vaccination schedule in providing complete protection against all CPV variants
  • Date Range: 2019 - 2022
  • Funding Body: University of Peradeniya
  • Position: Co-investigator

  • Project Title: Multi Locus sequence typing (MLST) of avian pathogenic Escherichia coli.
  • Date Range: 2011-2013
  • Funding Body: UNSW, Australia
  • Position: Co-investigator

  • Project Title: applying molecular diagnostics to zoonotic diseases (Mycobacterium)
  • Date Range: 2010
  • Funding Body: IAEA
  • Position: Project Manager, University of Peradeniya

  • Project Title: Development of a rapid test to diagnose fish Mycobacteriosis schedule in providing complete protection against all CPV variants
  • Date Range: 2008-2010
  • Funding Body: University of Peradeniya
  • Position: Principal investigatora

  • Project Title: Determination of core types of lipopolysaccharide of avian pathogenic E. coli and their immunogenicity
  • Date Range: 2004-2007
  • Funding Body: National Science Foundation
  • Position: Co-nvestigator

  • Active research grants:
  • Project Title: Analysis of multidrug resistant Extra intestinal pathogenic E. coli clones in humans and animals in Sri Lanka
  • Date Range: 2019-2022
  • Funding Body: National Research Council
  • Position: Principal Investigator
  • Position MPhil. / PhD. Current Completed
    Co supervisor MPhil 1
    Supervisor MPhil 4 1
    Completed supervisions: Ms. R. A. Edirisinghe (MPhil). Occurrence of nontuberculous mycobacteria in different aquatic sources in Sri Lanka

    • Gamage, B.G.S.S., Dissanayake, D.R.A., Prasada, D.V.P, I.D. Silva, (2020). Risk, prognosis and causality of parvo viral enteritis in dogs in Sri Lanka. Comparative Immunology, Microbiology and Infectious Diseases, p.101496.

    • Neelawala, D. Dissanayake D. R. A., Prasada, D.V. P., Silva , I. D. (2020). Analysis of risk factors associated with recurrence of canine babesiosis caused by Babesia gibsoni. Comparative Immunology, Microbiology and Infectious Diseases. Accepted for publication,

    • Sutton, R., Venn, N.C., Law, T., Boer, J.M., Trahair, T.N., Ng, A., Den Boer, M.L., Dissanayake, A., Giles, J.E., Dalzell, P. and Mayoh, C. (2017). A risk score including microdeletions improves relapse prediction for standard and medium risk precursor B‐cell acute lymphoblastic leukaemia in children. British Journal of Haematology. doi: 10.1111/bjh.15056.

    • E. A. Roshani Edirisinghe, D. R. Anuruddhika Dissanayake, Charmalie L. Abayasekera, Appudurai Arulkanthan( 2017). Efficacy of calcium hypochlorite and ultraviolet irradidation against Mycobacterium fortuitum and Mycobacterium Marinum. International Journal of Mycobacteriology 6, 311-314.

    • Dissanayake, D. R. A., Perera, V., Jagoda, S.S.S.De.S.Jagoda, Edirisinghe, E.A.R., Arulkanathan, A. (2017) Characterisation of Non-tuberculous Mycobacteria Isolated from Apparently Healthy and Diseased Fresh Water Ornamental Fish in Sri Lanka. Asian Fisheries Science, 30, 118-129.

    • Mary Sartor, Draga Barbaric, Tamara Law, D R Anuruddhika Dissanayake, Nicola C Venn, Mawar Karsa,Sue Wong, Murray D Norris, Petra Ritchie, Tamas Revesz, Peter J Shaw, Ken Bradstock,Luciano Dalla Pozza, Toby N Trahair, Rosemary Sutton (2015). Improved Concordance of Minimal Residual Disease Measurements by Quantitative PCR and 10-color flow cytometry in Pediatric Acute Lymphoblastic Leukemia. Blood Amer Soc hematology. Vol. 126.

    • Sutton, R., Shaw, P.J., Venn, N.C., Law, T., Dissanayke, Anuruddhika., Kilo, T., Haber, M., Norris , M.D., Fraser, C., Alvaro F., Revez, T., Trahair, T., Dalla Pozza, L., Marshall, G.M., O’Brien, T.A. (2015). Persistent MRD before and after allogeneic BMT predicts relapse in children with acute lymphoblastic Leukaemia. British Journal of Heamatology, 168(3), 395-404.

    • Dissanayake, D.R.A, Octavia, S., Lan, R (2014). Population structure and virulent content of avian pathogenic Escherichia coli isolated from outbreaks in Sri Lanka. Veterinary Microbiology. 168(403-412).

    • Edirisinghe E.A.R., Dissanayake, D.R.A., Abayasekara, C.L., Arulkanthan, A. (2014). Occurrence of nontuberculous mycobacteria in aquatic sources of Sri Lanka. International Journal of Mycobacteriology.

    • Dissanayake, D. R. A., Wijewardana, T.G., Gunawardena, G. A., Poxton, I. R. (2010) Potential use of liposome encapsulated mixture of lipopolysaccharide core types (R1,R2, R3, and R4) of Escherichia coli in controlling colisepticaemia in chickens. Journal of medical microbiology, 59; 100-107.

    • Dissanayake, D. R. A., Wijewardana, T.G., Gunawardena, G. A., Poxton, I. R. (2008). Distribution of lipopolysaccharide core types among avian pathogenic Escherichia coli in relation to the major phylogenetic groups Veterinary microbiology. 132, 355-363.

    • Matibag, G. C., Ditangco, R.A., Kamigaki, T., Kumarasiri, P V. R., Wijewardana, T. G., Kalupahana, A. W., Dissanayake, D. R. A., de Silva, D. D. N., Gunawardena, G. S. P. de S., Kanda, K., Y. O., Tamashiro, H. (2008). Community based evaluation of health seeking behavior of people with animal bite injuries in a district of Sri Lanka. Journal of international health. 23, 173-179.

    • Matibag, G. C., Kamigaki, T., Wijewardana, T. G., Kumarasiri, P V. R., Kalupahana, A. W., Dissanayake, D. R. A., de Silva, D. D. N., Gunawardena, G. S. P. de S., Obayashi,Y., Kanda, K., Y. O., Tamashiro, H. (2007). Knowledge, attitudes, and practices survey of rabies in a community in Sri Lanka. Environmental health and preventive medicine. 12, 84–89.

    • Atapattu, U., Dissanayake, D.R. A., Silva, I.D., Bulumulla, D.G.S.S., Neelwala, N.G.D.A.K. and Wijekoon, T., 2017. Acute heaptozoonosis caused by Hepatozoon canis in dogs in Sri Lanka. Sri Lanka Veterinary Journal, 64(1A).

    • Jagoda, S.D.S., Dissanayake, D.M.S.G., Ranathunga, R.A.D.S., Dissanayake, D.R.A. and Arulkanthan, A., 2017. Piscine mycobacteriosis in gold fish (Carassius auratus) and Koi carp (Cyprinus carpio): two case reports. Sri Lanka Veterinary Journal, 64(1A).

    • Dissanayake, D.R.A., Silva, I.D., Gamage, S., Sonnadara, D., Bandara, M.R.B.N., Alokabandara, S.S., Jayapani, V.P. and Jayaweera, W., 2016. Feline Panleukopenia virus infection in a captive-bred Bengal tiger (Panther tigris tigris) and a leopard (Panthera pradus). Sri Lanka Veterinary Journal, 63(2).

    • Dissanayake, D.R.A., Silva, I.D., Senapathi, Y.U., de Silva, D.D.N., Mallikarachchi, M.D.H.S., Gunathilaka, W.G.D.A., Kumara, W.R.B., Rajapaksha, E. and Fernando, W.C.R., 2016. The diagnosis and treatment of acquired Myasthenia Gravis in two adult dogs using oral neostigmine bromide. Sri Lanka Veterinary Journal, 63(1).

    • Dissanayake, D.R.A. and Wijewardena, T.G., 2016. Immunogenicity of Escherica coli rough mutant bacterin in chicken. Sri Lanka Veterinary Journal, 63(1).

    • Freshly eaten vegetable; a source of food borne pathogens? A.G.D.D.Silva. C L Abayasekara, D. R. A. Dissanayake (2013). Ceylon journal of Science (Bio. Sci). 42 (2), 95-99.

    • Wijewardana, T.G., Ranasinghe, G .K. M.C. Dissanayake, D. R. A., (2004). An outbreak of erysipelas in a poultry breeder farm in Kandy district Sri Lanka Veterinary Journal. 51, 5-7.
    • Gamage, B. G. S. S., Silva, I. D., Prasada, D. V. P., Dissanayake D. R. A. Identification of Variants of Canine Parvovirus and Analysis of Risk Factors in Parvoviral Enteritis among Vaccinated Dogs. Peradeniya University International Research sessions. 11th -12th September 2019. paper no 3.45

    • Neelawela, N. G. D. A. K., Dissanayake, D. R. A., Silva., I. D. Haematological Observations of Concurrent Infections of Babesiosis and other Tick-borne Haemoparasitism in Dogs. Peradeniya University International Research sessions. 11th & 12th September 2019. Paper no. 1.71

    • Gamage, B. G. S. S., Silva, I. D., Dissanayake, D. R. A. Molecular characterisation of canine parvo virus type 2c in Sri Lanka. 71st Annual Scientic sessions of Sri Lanka Veterinary Association. 28th June, 2019. Oak Ray Regency, Kandy.1

    • Sutton, R Nicola C Venn, Walter Muskovic, Tamara Law Toby N Trahair, Anthea Ng, D R Anuruddhika Dissanayake ,Jodie E Giles, Tamas Revesz, Glenn M Marshall, Luciano Dalla Pozza. Inclusion of key microdeletions improves risk assessment for non-high risk BCP-ALL. ANZHOG 2018. Sydney, Australia.
    • S. Gamage, D.R.A. Dissanayake, I.D. Silva, V.P. Priyanka Jayapani (2017). Molecular characterization of canine parvo virus in Sri Lanka. International Research session, University of Peradeniya, 24th November 2017.

    • A.M.U. Atapattu, W. R.B. Kumara, D.R.A.Dissanayake,Ultrasonographic changes of pancrease and peripancreatic structures of dogs attributed to ingestion of durian, Annual Scientific Sessions of Sri Lanka Veterinary Association, 15th May 2017. Pp55.

    • D. R. A .Dissanayake, I. D. Silva, Y. U. de Silva Senapathi, K. K. Sumanasekara, W.R.B Kumara, P. M. Dunukearachchi, W.C.R. Fernando, A. S. Lenagala and S. De Silva. The prognostic significance of blood leukocyte counts at the onset of hemorrhagic diarrhoea in parvo viral enteritis among immunized pups. Annual Scientific Sessions of Sri Lanka Veterinary Association, 15th May 2016. pp .

    • Wijayawardhane, K.A.N., Dissanayake, D.R.A., Kumara, U.G.V.S., Dharmasuriya, J.Y.C. Fernando, W.C. R., Jayapani, V. P. P.. Colonization of Methicillin-resistant Staphylococcus aureus in dogs and dog handlers. Annual Scientific Sessions of Sri Lanka Veterinary Association, 15th May 2016. pp .

    • Sartor M; Barbaric D; Law T; Dissanayake A; Venn NC; Karsa M; Wong SWJ; Norris MD; Revesz T; Ritchie P; Shaw PJ; Bradstock KF; Pozza LD; Trahair TN; Sutton R, 2015, 'Improved Concordance of Minimal Residual Disease Measurements By Quantitative PCR and 10-Color Flow Cytometry in Pediatric Acute Lymphoblastic Leukemia', , presented at 57th Annual Meeting of the American-Society-of-Hematology, Orlando, FL, 5 - 8 December 2015.

    • W. Muskovic, N. C. Venn, J. E. Giles, T. Law, D. R. A. Dissanayake, T. N. Trahair and R. Sutton. Dual purpose generic MRD Markers based on the PAR1 deletion and IKZF1 microdeletions in BCP-ALL. 4th symposium of European scientific foundation on laboratory hemato oncology (ESHLO) on new developments in MRD diagnostics. At World Trade Centre, Surich, Switzerland on 5-6 November 2015.

    • Sartor, M., Law, T., Dissanyake, A., Venn, N.C., Karsa, M., Trahair,T., Barbaric, D., Dalla Pozza, L., Norris,M.D., Bradstock.K, Sutton, R . Comparison of minimal residual disease (MRD) quantitation by ten colour flow cytometry and real time PCR in acute lymphoblastic leukemia. 24th Annual Scientific Meeting, Australian Society for Medical Research, Sydney, Australia. 2014

    • Sutton, R. Sartor, M., Law, T., Dissanyake, A., Venn, N.C., Karsa, M., Trahair,T., Barbaric, D., Dalla Pozza, L., Norris,M.D., Bradstock.K., Use of 10-colour flow to detect MRD in ALL improves concordance with PCR-MRD results. 9th Childhood Leukemia Symposium. Clarion Congress Hotel Prague Freyova 33, 190 00 Prague 9. Czech Republic. 28th April to 29th April, 2014.

    • Sutton, R., Muskovic, W., Venn,N.C., Giles,J.E., Law, T., Dissanyake, A., Trahair,T., Marshall,G. M., L Dalla Pozza, L. Dual purpose RQ-PCR based tests for CRLF2 and IKZF1 gene deletions in ALL. 9th Childhood Leukemia Symposium. Clarion Congress Hotel Prague Freyova 33, 190 00 Prague 9. Czech Republic. 28th April to 29th April, 2014.

    • Muskovic, W., Venn, N.C., Giles,J .E., Law, T., Dissanayake, A., Trahair,T., and Sutton, R. (2014). New MRD markers based on the CRLF2 and IZF1 gene deletions for ALL patients. New Directions in Leukemia Research (NDRL) meeting. Sunshine Coast, Queensland, Australia. 30th March to 2nd April 2014.

    • Muskovic, W., Venn,N.C., Giles,J.E., Law, T., Dissanayake, A., Trahair,T., Marshall, G., Dalla Pozza, L., and Sutton, R. Dual purpose RQ-PCR based tests for CRLF2 and IKZF1 gene deletions in ALL. 23rd Annual Scientific Meeting, Australian Society for Medical Research, Sydney, Australia. 2013 .

    • Perera, D.V.M., Dissanayake, D.R.A., Arulkanthan, A., Jagoda, S. S.de. S., Edirisinghe, E. A. R. (2010). Identification of fish pathogenic mycobacterium Species by PCR-restriction fragment length polymorphism of the rpoB gene. In Proceedings of the Peradeniya University Research Sessions, Sri Lanka. Vol 15, December 16, 2010. 320-322.

    • Jagoda S. S. S. de S. Wijewardena T. G., Arulkantha A., Dissanayake, D. R. A. (2010). Isolation, identification and in vitro antibacterial susceptibility of Aeromonas species causing septicaemia in fresh water ornamental fish in Sri Lanka. Proceedings of the 62nd annual Scientific Session of the Sri Lanka Veterinary Association.

    • Dissanayake, D.R.A., Wijewardena, T.G., Arulkanthan, A., Buddhika, M.D.P. and Jagoda, S.S.S.de.S. ( 2009). Occurrence of mycobacteria in various organs of clinically affected and apparently healthy guppies (Poecillia reticulate). Proceedings, Peradeniya University research sessions. 2009. 14 (1), 331-333.

    • Dissanayake, D.R.A., Wijewardana, T.G., Gunawardena, G.A and Poxton, I.R (2008).The use of liposome encapsulated LPS core vaccine to control E. coli infections in chickens. 60th Annual Convention and Scientific Sessions of Sri Lanka Veterinary Association. 29-30 May 2008. pp.16.

    • Dissanayake, D.R.A., Wijewardana, T.G., Gunawardena, G.A and Poxton, I.R (2007). Use of liposome incorporated complete lipopolysaccharide core types R1, R2, R3 and R4 to control E. coli infection in chickens. Proceedings of scientific sessions of international poultry exhibition and conference. Sri Lanka exhibition and conventional center. 22-23 October 2007. pp.48.

    • Dissanayake, D.R.A., Wijewardana, T.G., Gunawardena, G.A and Poxton, I.R (2007). Occurrence of temperature sensitive haemagglutinin (TSH) increase serum survival (ISS) and Col V plasmid (CVA C) genes in chicken E. coli in relation to serum resistance, Proceedings of the Peradeniya University Research Sessions, 12, Part I, pp 166.

    • Dissanayake, D. R. A., Wijewardana, B.D.R, Wijewardana, T. G., S. P De S Gunawardana and Mallawarachchi, M.A.J.S.(2005). Acute pulmonary aspergillosis in a calf – a case report, Annual Convention and Scientific Sessions of Sri Lanka Veterinary Association, 13- 14 May. 2005. pp 11.

    • Dissanayake, D.R.A., Wijewardana, T.G., Abeynayake, P., Fernando, C.P.L and Wanigasinghe, W.B.A.B (2003). A serological and biochemical characterization of Salmonella from poultry at the microbiology diagnostic laboratory. In: Proceedings of the Peradeniya University Research Sessions. Sri Lanka. 8, October 23, 2003.

    • Wijewardena, T.G., Arulkanthan, A, Gunawardena, GS.P.De.S, Dissanayake, D.R.A., Kalupahana, AW. And Jagoda, S.S.S. De S. (2009). Laboratory procedures for fish diseases diagnosis and research ISBN 978-955-0185-00-9.