Department of Basic Veterinary Sciences

Faculty of Veterinary Medicine & Animal Science

saumya

Dr.Y A M Saumya Wickramasinghe

Senior Lecturer (Grade II)

Office Address :

Department of Basic Veterinary Sciences

Faculty of Veterinary Medicine & Animal Science,

University of Peradeniya, Peradeniya 20400, Sri Lanka

Email : saumyawicks@gmail.com  
Phone :  (official and mobile): (official and mobile): 0812395831/0777900896
Education :
  • Bachelor of Veterinary Science (BVSc), University of Peradeniya, Sri Lanka (1997-2003).
  • MSc Animal Science, Oklahoma State University, Stillwater, OK (2004-2006)
  • Specialization in Animal Genetics and Biochemistry, Thesis title: “Single nucleotide analysis of genes expressed in bovine adipose tissue”
  • PhD Animal Biology, University of California Davis, Davis, CA (2006-2011)
  • Specialization in Molecular Genetics and Lactation Biology, Thesis title: “Trancriptome profiling of bovine milk with special emphasis on oligosaccharide metabolism genes

  1. Travel award to attend the Consortium of Universities for Global Health 2018
  2. Air commodore Dr. R.M.P.H. Dassanayake award for the best paper and the presentation in animal production at the 68th annual scientific sessions of the Sri Lanka Veterinary Association (SLVA) – 2017
  3. Air commodore Dr. R.M.P.H. Dassanayake award for the best paper and the presentation in animal production at the 68th annual scientific sessions of the Sri Lanka Veterinary Association (SLVA) – 2016
  4. President’s award for Scientific Publication awarded by the National Research Council of Sri Lanka – 2016
  5. Academic without borders-USA grant awarded for the project “One Health Faculty Development to Improve Teaching and Learning Strategies” – 2016
  6. Academic without borders-USA grant awarded for the project “One Health Approach to course development and implementation” – 2015
  7. Austin Eugene Lyons Graduate Research Scholarship for academic year 2008, 2009 and 2010
  8. National Milk Producers Federation Graduate Student Paper Presentation Contest in Dairy Production: PhD division – 2010
  9. Student travel award – International Milk Genomic Consortium -2010
  10. P.E.O. International Peace Scholarship for graduate studies – 2007, 2008



  1. Biochemistry to first year Veterinary Undergraduate Students
  2. Nutrition to Second year Veterinary Undergraduate Students
  3. Bioinformatics module of Experimental Biotechnology MSc program in Postgraduate Institute of Science, University of Peradeniya.



  1. Next generation sequencing technologies to study the pathogenies of CKDU
  2. Study on elephant fecal microbiome, hot water spring microbiome and water microbiome
  3. RNA sequencing and gene expression
  4. Identification of genetic markers to improve the dairy cattle industry in Sri Lanka


Position Current completed
Project Leader 1 2
Completed projects:
  • Principal Investigator, “Genotyping of bovine milk protein genes using the tetra-primer ARMS-PCR technique” –University of Peradeniya Research Grants and International Research center of University Peradeniya – Year 2014-2017
  • Active research grants:
  • Principal Investigator ,“Insight in to pathogenesis of chronic kidney disease of unknown etiology (CKDu): RNA-Seq based transcriptome analysis and SNP profiling” –National Research Council of Sri Lanka – Year 2015-2019

  • Position MPhil. / PhD. current completed
    Co supervisor MPhil 1 1
    Supervisor MPhil 2 1
    Completed supervisions:
  • Ruwini Rupasinghe, MPhil
  • Ayesha Salgado MPhil

  • PEER-REVIEWED PUBLICATIONS

    1. Boudry, G., M K. Hamilton, M. Chichlowski, S. Wickramasinghe, D. Barile, K. M Kalanetra, D. A. Mills and H. E Raybould (2017). Bovine milk oligosaccharides decrease gut permeability and improve inflammation and microbial dysbiosis in diet-induced obese mice. Journal of Dairy Science .
    2. Wickramasinghe S, Pacheco SA, Lemay D and Mills D (2015) Bifidobacteria grown on human milk oligosaccharides downregulate the expression of inflammation-related genes in Caco-2 cells. BMC Microbiology 15(1):172.
    3. Wickramasinghe S, Cánovas A, Rincón G and Medrano JF (2014) RNA-Sequencing: A tool to explore new frontiers in animal genetics. Livestock Science 166: 206-216.
    4. Khaldi N, Vijayakumar V, Dallas DC, Guerrero A, Wickramasinghe S, Smilowitz JT, Medrano JF, Lebrilla CB, Shields DC and German JB (2014) Predicting the important enzyme players in human breast milk digestion. J Agric Food Chemistry 62(29):7225-32.
    5. Wickramasinghe S, Rincon G, Islas-Trejo A and Medrano JF (2012) Transcriptional profiling of bovine milk using RNA sequencing. BMC Genomics 13:45
    6. Barboza M, Pinzon J, Wickramasinghe S, Froehlich JW, Moeller I, Smilowitz JT, Ruhaak LR, Huang J, Lönnerdal B, German JB, Medrano JF, Weimer BC and Lebrilla CB (2012) Glycosylation of human milk lactoferrin exhibits dynamic changes during early lactation enhancing its role in pathogenic bacteria-host interactions. Molecular & Cellular Proteomics 11(6).
    7. Wickramasinghe S, Hua S, Rincon G, Islas-Trejo A, German JB, Lebrilla CB and Medrano JF (2011) Transcriptome Profiling of Bovine Milk Oligosaccharide Metabolism Genes Using RNA-Sequencing. PLoS ONE 6(4): e18895
    8. Wickramasinghe S and Medrano JF (2011) Primer on genes encoding enzymes in sialic acid metabolism in mammals. Biochimie 93:1641-1646.
    9. Wickramasinghe S, Rincon G and Medrano JF (2011) Variants in the pregnancy-associated plasma protein-A2 gene on Bos taurus autosome 16 are associated with daughter calving ease and productive life in Holstein cattle. Journal of Dairy Science 94:1552-1558.
    10. Cánovas A, Rincon G, Islas-Trejo A, Wickramasinghe S and Medrano JF (2010) SNP discovery in the bovine milk transcriptome using RNA-Seq technology. Mammalian Genome 21:592-598
    REVIEW OF DATABASES
  • Sialic acid metabolism in Reactome data base (2014)
  • SELECTED PEER-REVIEWED CONFERENCE PROCEEDINGS
    1. Ruwini K. Rupasinghe and Saumya Wickramasinghe (2017) Study on Beta casein A1 and A2 polymorphism in Ayrshire and Holstein Frisian dairy cattle populations, 69th annual scientific sessions of the Sri Lanka Veterinary Association, Kandy, Sri Lanka.
    2. Ruwini K. Rupasinghe and Saumya Wickramasinghe (2016) Polymorphism of casein cluster genes in Ayrshire and Holstein Friesian dairy herds in Sri Lanka, 68th annual scientific sessions of the Sri Lanka Veterinary Association, Kandy, Sri Lanka.
    3. Ruwini Rupasinghe and Saumya Wickramasinghe (2015) Genotyping of bovine κ-casein gene variants in Sri Lankan dairy cows by tetra-primer ARMS-PCR technique, , Plant and Animal Genome Asia conference, Singapore.
    4. Wickramasinghe S, Pacheco A and Mills D (2013). Characterization of the interactions between milk glycan-consuming bifidobacteria and the host epithelium: International Milk Genomic Consortium, Davis CA, USA .
    5. Boudry G, Hamilton MK, Kalenetra KM, Wickramasinghe S, Pacheco AR , Mills DA and Raybould HE (2013). Bien nourrir son probiotique : le probiotique Bifidobacterium infantis consommé avec des oligosaccharides de lait de vache mais pas de l’inuline restaure l’homéostasie intestinale de souris obèses : Journées Francophones de Nutrition (JNF), Bordeaux, France.
    6. Wickramasinghe S, Rincon G, Islas-Trejo A. and Medrano, JF (2012) High throughput SNP discovery in the bovine lactome by RNA sequencing: Plant and Animal Genome conference, San Diego, CA, USA.
    7. Wickramasinghe S, Rincon G, Islas-Trejo A and Medrano JF (2011) Analysis of the bovine milk transcriptome by RNA sequencing: ADSA meeting, New Orleans, USA.
    8. Huang J, Barboza M, Wickramasinghe S, Wu S, Medrano J, Lebrill CA (2011) Correlating Glycan Expression with Gene Expression in Milk Glycoproteins : ASMS, Denver Colorado, USA.
    9. Wickramasinghe S., Rincon G., Islas-Trejo A and Medrano JF (2011) Analysis of the Milk Somatic Cell Transcriptome of Transition and Late Lactation Holstein Cows By RNA-Sequencing: Plant and Animal Genome conference, San Diego, CA, USA.
    10. Rincon, G., Wickramasinghe S., Islas-Trejo A and Medrano JF (2011) Comparison Of The Bovine Milk Somatic Cell And The Mammary Gland Transcriptome Using RNA-Sequencing Technology, Plant and Animal Genome conference, San Diego, CA, USA.
    11. Wickramasinghe, S, Rincon, G, Islas-Trejo A and Medrano JF (2010) Analysis of the Milk Transcriptome of Transition and Late Lactation Holstein Cows by Next Generation Sequencing Technology. International Milk Genomic Consortium, Davis CA, USA .
    12. Vasudevan-Pillai A, Guo X, Kupfer DM, Krehbiel CR, Wickramasinghe S, Ayoubi P, Roe, BA, DeSilva U (2006) Differential Expression Analysis of Adipogenesis in Cattle, Plant and Animal Genome conference, San Diego, CA, USA.
    SELECTED ORAL PRESENTATIONS
    1. Wickramasinghe S (2015) Application of RNA-Seq Technology in the Field of Animal Biotechnology , Plant and Animal Genome conference Asia, Singapore.
    2. Wickramasinghe S., Hua S., Rincon G, Islas-Trejo, A, Lebrilla, CB and Medrano JF (2010) Expression analysis of genes of sialic acid metabolism in transition and late lactation Holstein cows using microarrays and RNA sequencing. ADSA®-PSA-AMPA-CSAS-ASAS Joint Annual Meeting, Denver, Colorado.
    3. Wickramasinghe S., Rincon G., Islas-Trejo A and Medrano, JF (2010) Analysis of the Milk Transcriptome of Transition and Late Lactation Holstein Cows by Next Generation Sequencing Technology. International Milk Genomic Consortium, Davis CA.